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Discovery libraries targeting the major enzyme classes: the serine hydrolases
Two libraries of modestly reactive ureas containing either electron-deficient acyl anilines or acyl pyrazoles were prepared and are reported as screening libraries for candidate serine hydrolase inhibitors. Within each library is a small but powerful subset of compounds that serve as a chemotype fra...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4130767/ https://ncbi.nlm.nih.gov/pubmed/25037918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.06.063 |
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