Yap Tunes Airway Epithelial Size and Architecture by Regulating the Identity, Maintenance, and Self-renewal of Stem Cells

Our understanding of how stem cells are regulated to maintain appropriate tissue size and architecture is incomplete. We show that Yap is required for the actual maintenance of an adult mammalian stem cell. Without Yap, adult airway basal stem cells are lost through their unrestrained differentiatio...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhao, Rui, Fallon, Timothy R., Saladi, Srinivas Vinod, Pardo-Saganta, Ana, Villoria, Jorge, Mou, Hongmei, Vinarsky, Vladimir, Gonzalez-Celeiro, Meryem, Nunna, Naveen, Hariri, Lida P., Camargo, Fernando, Ellisen, Leif W., Rajagopal, Jayaraj
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130488/
https://ncbi.nlm.nih.gov/pubmed/25043474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.06.004
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