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Yap Tunes Airway Epithelial Size and Architecture by Regulating the Identity, Maintenance, and Self-renewal of Stem Cells

Our understanding of how stem cells are regulated to maintain appropriate tissue size and architecture is incomplete. We show that Yap is required for the actual maintenance of an adult mammalian stem cell. Without Yap, adult airway basal stem cells are lost through their unrestrained differentiatio...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Zhao, Rui, Fallon, Timothy R., Saladi, Srinivas Vinod, Pardo-Saganta, Ana, Villoria, Jorge, Mou, Hongmei, Vinarsky, Vladimir, Gonzalez-Celeiro, Meryem, Nunna, Naveen, Hariri, Lida P., Camargo, Fernando, Ellisen, Leif W., Rajagopal, Jayaraj
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130488/
https://ncbi.nlm.nih.gov/pubmed/25043474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.06.004
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