Developmental history provides a roadmap for the emergence of tumor plasticity

We show that the loss or gain of transcription factor programs that govern embryonic cell fate specification is associated with a form of tumor plasticity characterized by the acquisition of alternative cell fates normally characteristic of adjacent organs. In human non-small cell lung cancers, down...

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Bibliographic Details
Published in:Dev Cell
Main Authors: Tata, Purushothama Rao, Chow, Ryan Dz-Wei, Saladi, Srinivas Vinod, Tata, Aleksandra, Konkimalla, Arvind, Bara, Anne, Montoro, Daniel, Hariri, Lida P., Shih, Angela R., Mino-Kenudson, Mari, Mou, Hongmei, Kimura, Shioko, Ellisen, Leif W., Rajagopal, Jayaraj
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875457/
https://ncbi.nlm.nih.gov/pubmed/29587142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.02.024
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