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Modulation of Platelet Activation and Thrombus Formation Using a Pan-PI3K Inhibitor S14161
The phosphatidylinositol 3–kinase (PI3K) signaling pathway is critical in modulating platelet functions. In the present study, we evaluated the effect of S14161, a recently identified pan-class I PI3K inhibitor, on platelet activation and thrombus formation. Results showed that S14161 inhibited huma...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4130470/ https://ncbi.nlm.nih.gov/pubmed/25115838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102394 |
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