The pyrrolidinoindoline alkaloid Psm2 inhibits platelet aggregation and thrombus formation by affecting PI3K/Akt signaling

AIM: Psm2, one of the pyrrolidinoindoline alkaloids isolated from whole Selaginella moellendorffii plants, has shown a potent antiplatelet activity. In this study, we further evaluated the antiplatelet effects of Psm2, and elucidated the underlying mechanisms. METHODS: Human platelet aggregation in...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Su, Xing-li, Su, Wen, Wang, Ying, Wang, Yue-hu, Ming, Xin, Kong, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5022097/
https://ncbi.nlm.nih.gov/pubmed/27424653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.52
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