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Defects in secretion, aggregation, and thrombus formation in platelets from mice lacking Akt2
Prior studies have shown that PI3Ks play a necessary but incompletely defined role in platelet activation. One potential effector for PI3K is the serine/threonine kinase, Akt, whose contribution to platelet activation was explored here. Two isoforms of Akt were detected in mouse platelets, with expr...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC324545/ https://ncbi.nlm.nih.gov/pubmed/14755341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420267 |
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