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Defects in secretion, aggregation, and thrombus formation in platelets from mice lacking Akt2

Prior studies have shown that PI3Ks play a necessary but incompletely defined role in platelet activation. One potential effector for PI3K is the serine/threonine kinase, Akt, whose contribution to platelet activation was explored here. Two isoforms of Akt were detected in mouse platelets, with expr...

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書目詳細資料
發表在:J Clin Invest
Main Authors: Woulfe, Donna, Jiang, Hong, Morgans, Alicia, Monks, Robert, Birnbaum, Morris, Brass, Lawrence F.
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2004
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC324545/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14755341/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI20267
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