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Defects in secretion, aggregation, and thrombus formation in platelets from mice lacking Akt2
Prior studies have shown that PI3Ks play a necessary but incompletely defined role in platelet activation. One potential effector for PI3K is the serine/threonine kinase, Akt, whose contribution to platelet activation was explored here. Two isoforms of Akt were detected in mouse platelets, with expr...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC324545/ https://ncbi.nlm.nih.gov/pubmed/14755341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420267 |
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