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Defective thrombus formation in mice lacking coagulation factor XII

Blood coagulation is thought to be initiated by plasma protease factor VIIa in complex with the membrane protein tissue factor. In contrast, coagulation factor XII (FXII)–mediated fibrin formation is not believed to play an important role for coagulation in vivo. We used FXII-deficient mice to study...

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書誌詳細
主要な著者: Renné, Thomas, Pozgajová, Miroslava, Grüner, Sabine, Schuh, Kai, Pauer, Hans-Ulrich, Burfeind, Peter, Gailani, David, Nieswandt, Bernhard
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213000/
https://ncbi.nlm.nih.gov/pubmed/16009717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050664
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