Defective thrombus formation in mice lacking coagulation factor XII

Blood coagulation is thought to be initiated by plasma protease factor VIIa in complex with the membrane protein tissue factor. In contrast, coagulation factor XII (FXII)–mediated fibrin formation is not believed to play an important role for coagulation in vivo. We used FXII-deficient mice to study...

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Huvudupphovsmän: Renné, Thomas, Pozgajová, Miroslava, Grüner, Sabine, Schuh, Kai, Pauer, Hans-Ulrich, Burfeind, Peter, Gailani, David, Nieswandt, Bernhard
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2005
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213000/
https://ncbi.nlm.nih.gov/pubmed/16009717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050664
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