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Misregulation of Alternative Splicing Causes Pathogenesis in Myotonic Dystrophy

Myotonic dystrophy (DM), the most common form of adult onset muscular dystrophy, affects skeletal muscle, heart, and the central nervous system (CNS). Mortality results primarily from muscle wasting and cardiac arrhythmias. There are two forms of the disease: DM 1 and DM 2. DM 1, which constitutes 9...

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Autori principali: Muge Kuyumcu-Martinez, N., Cooper, Thomas A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127983/
https://ncbi.nlm.nih.gov/pubmed/17076268
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