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Misregulation of Alternative Splicing Causes Pathogenesis in Myotonic Dystrophy

Myotonic dystrophy (DM), the most common form of adult onset muscular dystrophy, affects skeletal muscle, heart, and the central nervous system (CNS). Mortality results primarily from muscle wasting and cardiac arrhythmias. There are two forms of the disease: DM 1 and DM 2. DM 1, which constitutes 9...

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Bibliographic Details
Main Authors: Muge Kuyumcu-Martinez, N., Cooper, Thomas A.
Format: Artigo
Language:Inglês
Published: 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127983/
https://ncbi.nlm.nih.gov/pubmed/17076268
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