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Intact and N- or C- terminal end truncated AQP0 function as open water channels and cell-to-cell adhesion proteins: End truncation could be a prelude for adjusting the refractive index of the lens to prevent spherical aberration

PURPOSE: Investigate the impact of natural N- or C-terminal post-translational truncations of lens mature fiber cell Aquaporin 0 (AQP0) on water permeability (Pw) and cell-to-cell adhesion (CTCA) functions. METHODS: The following deletions/truncations were created by site-directed mutagenesis (desig...

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書誌詳細
主要な著者: Kumari, S. Sindhu, Varadaraj, Kulandaiappan
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127142/
https://ncbi.nlm.nih.gov/pubmed/24821012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2014.05.002
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