Intact and N- or C- terminal end truncated AQP0 function as open water channels and cell-to-cell adhesion proteins: End truncation could be a prelude for adjusting the refractive index of the lens to prevent spherical aberration

PURPOSE: Investigate the impact of natural N- or C-terminal post-translational truncations of lens mature fiber cell Aquaporin 0 (AQP0) on water permeability (Pw) and cell-to-cell adhesion (CTCA) functions. METHODS: The following deletions/truncations were created by site-directed mutagenesis (desig...

Full description

Saved in:
Bibliographic Details
Main Authors: Kumari, S. Sindhu, Varadaraj, Kulandaiappan
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127142/
https://ncbi.nlm.nih.gov/pubmed/24821012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2014.05.002
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items