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C-Terminal End of Aquaporin 0 Regulates Lens Gap Junction Channel Function

PURPOSE: We reported previously that aquaporin 0 (AQP0) modulates lens fiber cell gap junction (GJ) channel function. The present study was conducted to find out whether the C-terminal end of AQP0 is involved in this regulation. METHODS: A mouse model, AQP0(ΔC/ΔC), was genetically engineered to expr...

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Dettagli Bibliografici
Pubblicato in:Invest Ophthalmol Vis Sci
Autori principali: Varadaraj, Kulandaiappan, Gao, Junyuan, Mathias, Richard T., Kumari, Sindhu
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Association for Research in Vision and Ophthalmology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6568327/
https://ncbi.nlm.nih.gov/pubmed/31195409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.19-26787
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