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Intact and N- or C- terminal end truncated AQP0 function as open water channels and cell-to-cell adhesion proteins: End truncation could be a prelude for adjusting the refractive index of the lens to prevent spherical aberration
PURPOSE: Investigate the impact of natural N- or C-terminal post-translational truncations of lens mature fiber cell Aquaporin 0 (AQP0) on water permeability (Pw) and cell-to-cell adhesion (CTCA) functions. METHODS: The following deletions/truncations were created by site-directed mutagenesis (desig...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4127142/ https://ncbi.nlm.nih.gov/pubmed/24821012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2014.05.002 |
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