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Structure of the C. elegans ZYG-1 cryptic polo box suggests a conserved mechanism for centriolar docking of Plk4 kinases

Plk4 family kinases control centriole assembly. Plk4s target to mother centrioles through an interaction between their cryptic polo box (CPB) and acidic regions in the centriolar receptors SPD-2/Cep192 and/or asterless/Cep152. Here, we report a crystal structure for the CPB of C. elegans ZYG-1, whic...

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書誌詳細
主要な著者: Shimanovskaya, Ekaterina, Viscardi, Valeria, Lesigang, Johannes, Lettman, Molly M., Qiao, Renping, Svergun, Dmitri I., Round, Adam, Oegema, Karen, Dong, Gang
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126857/
https://ncbi.nlm.nih.gov/pubmed/24980795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.05.009
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