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Direct Binding of SAS-6 to ZYG-1 Recruits SAS-6 to the Mother Centriole for Cartwheel Assembly

Assembly of SAS-6 dimers to form the centriolar cartwheel requires the ZYG-1/Plk4 kinase. Here we show that ZYG-1 recruits SAS-6 to the mother centriole independently of its kinase activity; kinase activity is subsequently required for cartwheel assembly. We identify a direct interaction between ZYG...

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Hlavní autoři:	Lettman, Molly M., Wong, Yao Liang, Viscardi, Valeria, Niessen, Sherry, Chen, Sheng-hong, Shiau, Andrew K., Zhou, Huilin, Desai, Arshad, Oegema, Karen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	2013
Témata:	Article
On-line přístup:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3655416/ https://ncbi.nlm.nih.gov/pubmed/23673331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.03.011
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Direct Binding of SAS-6 to ZYG-1 Recruits SAS-6 to the Mother Centriole for Cartwheel Assembly

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