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SAS-6 assembly templated by the lumen of cartwheel-less centrioles precedes centriole duplication
Centrioles are 9-fold symmetric structures duplicating once per cell cycle. Duplication involves self-oligomerization of the centriolar protein SAS-6, but how the 9-fold symmetry is invariantly established remains unclear. Here, we found that SAS-6 assembly can be shaped by preexisting (or mother) c...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4116473/ https://ncbi.nlm.nih.gov/pubmed/25017693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.05.008 |
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