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SAS-6 assembly templated by the lumen of cartwheel-less centrioles precedes centriole duplication

Centrioles are 9-fold symmetric structures duplicating once per cell cycle. Duplication involves self-oligomerization of the centriolar protein SAS-6, but how the 9-fold symmetry is invariantly established remains unclear. Here, we found that SAS-6 assembly can be shaped by preexisting (or mother) c...

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Detalhes bibliográficos
Main Authors: Fong, Chii Shyang, Kim, Minhee, Yang, T. Tony, Liao, Jung-Chi, Tsou, Meng-Fu Bryan
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116473/
https://ncbi.nlm.nih.gov/pubmed/25017693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.05.008
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