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Structure of the C. elegans ZYG-1 cryptic polo box suggests a conserved mechanism for centriolar docking of Plk4 kinases
Plk4 family kinases control centriole assembly. Plk4s target to mother centrioles through an interaction between their cryptic polo box (CPB) and acidic regions in the centriolar receptors SPD-2/Cep192 and/or asterless/Cep152. Here, we report a crystal structure for the CPB of C. elegans ZYG-1, whic...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4126857/ https://ncbi.nlm.nih.gov/pubmed/24980795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.05.009 |
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