Nalaganje...
Time-dependent diaryl ether inhibitors of InhA: SAR studies of enzyme inhibition, antibacterial activity, and in vivo efficacy
The diaryl ethers are a novel class of antituberculosis drug candidates that inhibit InhA, the enoyl-ACP reductase involved in the fatty acid biosynthesis (FASII) pathway, and have antibacterial activity against both drug-sensitive and drug-resistant strains of Mycobacterium tuberculosis. In the pre...
Shranjeno v:
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4126670/ https://ncbi.nlm.nih.gov/pubmed/24616444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201300429 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|