SciClone: Inferring Clonal Architecture and Tracking the Spatial and Temporal Patterns of Tumor Evolution

The sensitivity of massively-parallel sequencing has confirmed that most cancers are oligoclonal, with subpopulations of neoplastic cells harboring distinct mutations. A fine resolution view of this clonal architecture provides insight into tumor heterogeneity, evolution, and treatment response, all...

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Detalles Bibliográficos
Main Authors: Miller, Christopher A., White, Brian S., Dees, Nathan D., Griffith, Malachi, Welch, John S., Griffith, Obi L., Vij, Ravi, Tomasson, Michael H., Graubert, Timothy A., Walter, Matthew J., Ellis, Matthew J., Schierding, William, DiPersio, John F., Ley, Timothy J., Mardis, Elaine R., Wilson, Richard K., Ding, Li
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125065/
https://ncbi.nlm.nih.gov/pubmed/25102416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003665
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