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Synthesis and Structure activity relationships of EGCG Analogues, A Recently Identified Hsp90 Inhibitor

[Image: see text] Epigallocatechin-3-gallate (EGCG), the principal polyphenol isolated from green tea, was recently shown to inhibit Hsp90, however structure-activity relationships for this natural product have not yet been produced. Herein, we report the synthesis and biological evaluation of EGCG...

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Detalhes bibliográficos
Main Authors: Khandelwal, Anuj, Hall, Jessica, Blagg, Brian S. J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123816/
https://ncbi.nlm.nih.gov/pubmed/23834230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo401027r
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