Načítá se...

Natural Product Inspired Hsp90 N-Terminal Inhibitors for the Treatment of Cancer: From Bench to Bedside

The 90 kDa heat shock proteins (Hsp90) are responsible for the conformational maturation of nascent polypeptides and the rematuration of denatured proteins. Proteins dependent upon Hsp90 are associated with all six hallmarks of cancer. Upon Hsp90 inhibition, protein substrates are degraded via the u...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Med Res Rev
Hlavní autoři: Khandelwal, Anuj, Crowley, Vincent M., Blagg, Brian S. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659773/
https://ncbi.nlm.nih.gov/pubmed/26010985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/med.21351
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!