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Gambogic Acid, a Natural Product Inhibitor of Hsp90
A high-throughput screening of natural product libraries identified (−)-gambogic acid (1), a component of the exudate of Garcinia harburyi, as a potential Hsp90 inhibitor, in addition to the known Hsp90 inhibitor celastrol (2). Subsequent testing established that 1 inhibited cell proliferation, brou...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3103600/ https://ncbi.nlm.nih.gov/pubmed/21486005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np200029q |
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