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Anticancer Inhibitors of Hsp90 Function: Beyond the Usual Suspects

The 90-kDa heat-shock protein (Hsp90) is a molecular chaperone responsible for the stability and function of a wide variety of client proteins that are critical for cell growth and survival. Many of these client proteins are frequently mutated and/or overexpressed in cancer cells and are therefore b...

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Detalhes bibliográficos
Publicado no:Adv Cancer Res
Main Authors: Garg, Gaurav, Khandelwal, Anuj, Blagg, Brian S.J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892422/
https://ncbi.nlm.nih.gov/pubmed/26916001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.acr.2015.12.001
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