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Anticancer Inhibitors of Hsp90 Function: Beyond the Usual Suspects
The 90-kDa heat-shock protein (Hsp90) is a molecular chaperone responsible for the stability and function of a wide variety of client proteins that are critical for cell growth and survival. Many of these client proteins are frequently mutated and/or overexpressed in cancer cells and are therefore b...
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| Publicado no: | Adv Cancer Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5892422/ https://ncbi.nlm.nih.gov/pubmed/26916001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.acr.2015.12.001 |
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