ロード中...
Development of Phenyl Cyclohexylcarboxamides as a Novel Class of Hsp90 C-terminal Inhibitors
Inhibition of the heat shock protein 90 (Hsp90) C-terminus represents a promising therapeutic strategy for the treatment of cancer. Novobiocin, a coumarin antibiotic, was the first Hsp90 C-terminal inhibitor identified, however, it manifested poor anti-proliferative activity (SKBr3, IC(50) ~ 700 μM)...
保存先:
| 出版年: | Chemistry |
|---|---|
| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
|
| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5724527/ https://ncbi.nlm.nih.gov/pubmed/28940589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201703206 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|