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Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters

Although biosynthetic gene clusters (BGCs) have been discovered for hundreds of bacterial metabolites, our knowledge of their diversity remains limited. Here, we used a novel algorithm to systematically identify BGCs in the extensive extant microbial sequencing data. Network analysis of the predicte...

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書誌詳細
主要な著者: Cimermancic, Peter, Medema, Marnix H., Claesen, Jan, Kurita, Kenji, Wieland Brown, Laura C., Mavrommatis, Konstantinos, Pati, Amrita, Godfrey, Paul A., Koehrsen, Michael, Clardy, Jon, Birren, Bruce W., Takano, Eriko, Sali, Andrej, Linington, Roger G., Fischbach, Michael A.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123684/
https://ncbi.nlm.nih.gov/pubmed/25036635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.06.034
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