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Expansion of RiPP biosynthetic space through integration of pan-genomics and machine learning uncovers a novel class of lanthipeptides

Microbial natural products constitute a wide variety of chemical compounds, many which can have antibiotic, antiviral, or anticancer properties that make them interesting for clinical purposes. Natural product classes include polyketides (PKs), nonribosomal peptides (NRPs), and ribosomally synthesiz...

詳細記述

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書誌詳細
出版年:PLoS Biol
主要な著者: Kloosterman, Alexander M., Cimermancic, Peter, Elsayed, Somayah S., Du, Chao, Hadjithomas, Michalis, Donia, Mohamed S., Fischbach, Michael A., van Wezel, Gilles P., Medema, Marnix H.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794033/
https://ncbi.nlm.nih.gov/pubmed/33351797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3001026
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