Expansion of RiPP biosynthetic space through integration of pan-genomics and machine learning uncovers a novel class of lanthipeptides

Microbial natural products constitute a wide variety of chemical compounds, many which can have antibiotic, antiviral, or anticancer properties that make them interesting for clinical purposes. Natural product classes include polyketides (PKs), nonribosomal peptides (NRPs), and ribosomally synthesiz...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Kloosterman, Alexander M., Cimermancic, Peter, Elsayed, Somayah S., Du, Chao, Hadjithomas, Michalis, Donia, Mohamed S., Fischbach, Michael A., van Wezel, Gilles P., Medema, Marnix H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Methods and Resources
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794033/
https://ncbi.nlm.nih.gov/pubmed/33351797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3001026
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