Expansion of RiPP biosynthetic space through integration of pan-genomics and machine learning uncovers a novel class of lanthipeptides

Microbial natural products constitute a wide variety of chemical compounds, many which can have antibiotic, antiviral, or anticancer properties that make them interesting for clinical purposes. Natural product classes include polyketides (PKs), nonribosomal peptides (NRPs), and ribosomally synthesiz...

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Publicat a:PLoS Biol
Autors principals: Kloosterman, Alexander M., Cimermancic, Peter, Elsayed, Somayah S., Du, Chao, Hadjithomas, Michalis, Donia, Mohamed S., Fischbach, Michael A., van Wezel, Gilles P., Medema, Marnix H.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Methods and Resources
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794033/
https://ncbi.nlm.nih.gov/pubmed/33351797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3001026
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