Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters

Although biosynthetic gene clusters (BGCs) have been discovered for hundreds of bacterial metabolites, our knowledge of their diversity remains limited. Here, we used a novel algorithm to systematically identify BGCs in the extensive extant microbial sequencing data. Network analysis of the predicte...

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Hoofdauteurs: Cimermancic, Peter, Medema, Marnix H., Claesen, Jan, Kurita, Kenji, Wieland Brown, Laura C., Mavrommatis, Konstantinos, Pati, Amrita, Godfrey, Paul A., Koehrsen, Michael, Clardy, Jon, Birren, Bruce W., Takano, Eriko, Sali, Andrej, Linington, Roger G., Fischbach, Michael A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123684/
https://ncbi.nlm.nih.gov/pubmed/25036635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.06.034
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