Novel VCP modulators mitigate major pathologies of rd10, a mouse model of retinitis pigmentosa

Neuroprotection may prevent or forestall the progression of incurable eye diseases, such as retinitis pigmentosa, one of the major causes of adult blindness. Decreased cellular ATP levels may contribute to the pathology of this eye disease and other neurodegenerative diseases. Here we describe small...

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Main Authors: Ikeda, Hanako Ohashi, Sasaoka, Norio, Koike, Masaaki, Nakano, Noriko, Muraoka, Yuki, Toda, Yoshinobu, Fuchigami, Tomohiro, Shudo, Toshiyuki, Iwata, Ayana, Hori, Seiji, Yoshimura, Nagahisa, Kakizuka, Akira
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2014
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122966/
https://ncbi.nlm.nih.gov/pubmed/25096051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05970
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