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KUS121, a VCP modulator, attenuates ischemic retinal cell death via suppressing endoplasmic reticulum stress

Ischemic neural damages cause several devastating diseases, including brain stroke and ischemic retinopathies, and endoplasmic reticulum (ER) stress has been proposed to be the underlying mechanism of the neuronal cell death of these conditions. We previously synthesized Kyoto University substances...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hata, Masayuki, Ikeda, Hanako O., Kikkawa, Chinami, Iwai, Sachiko, Muraoka, Yuki, Hasegawa, Tomoko, Kakizuka, Akira, Yoshimura, Nagahisa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357950/
https://ncbi.nlm.nih.gov/pubmed/28317920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44873
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