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Neuoroprotective efficacies by KUS121, a VCP modulator, on animal models of retinal degeneration
Retinitis pigmentosa (RP) is one of the leading causes of adult blindness and has no established therapy. We have shown that valosin-containing protein (VCP) modulators, Kyoto University Substances (KUSs), ameliorated abnormally low ATP levels by inhibiting the ATPase of VCP, thereby protected sever...
Tallennettuna:
| Julkaisussa: | Sci Rep |
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| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4977562/ https://ncbi.nlm.nih.gov/pubmed/27503804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31184 |
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