Branched chain amino acids attenuate major pathologies in mouse models of retinal degeneration and glaucoma

Retinal neuronal cell death underlies many incurable eye diseases such as retinitis pigmentosa (RP) and glaucoma, and causes adult blindness. We have shown that maintenance of ATP levels via inhibiting ATP consumption is a promising strategy for preventing neuronal cell death. Here, we show that bra...

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Detalhes bibliográficos
Publicado no:Heliyon
Main Authors: Hasegawa, Tomoko, Ikeda, Hanako Ohashi, Iwai, Sachiko, Muraoka, Yuki, Tsuruyama, Tatsuaki, Okamoto-Furuta, Keiko, Kohda, Haruyasu, Kakizuka, Akira, Yoshimura, Nagahisa
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5857634/
https://ncbi.nlm.nih.gov/pubmed/29560458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2018.e00544
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