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VCP Is an Integral Component of a Novel Feedback Mechanism that Controls Intracellular Localization of Catalase and H(2)O(2) Levels

Catalase is a key antioxidant enzyme that catalyzes the decomposition of hydrogen peroxide (H(2)O(2)) to water and oxygen, and it appears to shuttle between the cytoplasm and peroxisome via unknown mechanisms. Valosin-containing protein (VCP) belongs to the AAA class of ATPases and is involved in di...

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Detalhes bibliográficos
Main Authors: Murakami, Katsuhiro, Ichinohe, Yuzuru, Koike, Masaaki, Sasaoka, Norio, Iemura, Shun-ichiro, Natsume, Tohru, Kakizuka, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573100/
https://ncbi.nlm.nih.gov/pubmed/23457492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056012
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