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Novel VCP modulators mitigate major pathologies of rd10, a mouse model of retinitis pigmentosa

Neuroprotection may prevent or forestall the progression of incurable eye diseases, such as retinitis pigmentosa, one of the major causes of adult blindness. Decreased cellular ATP levels may contribute to the pathology of this eye disease and other neurodegenerative diseases. Here we describe small...

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Библиографические подробности
Главные авторы: Ikeda, Hanako Ohashi, Sasaoka, Norio, Koike, Masaaki, Nakano, Noriko, Muraoka, Yuki, Toda, Yoshinobu, Fuchigami, Tomohiro, Shudo, Toshiyuki, Iwata, Ayana, Hori, Seiji, Yoshimura, Nagahisa, Kakizuka, Akira
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122966/
https://ncbi.nlm.nih.gov/pubmed/25096051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05970
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