Valosin-containing Protein (VCP) in Novel Feedback Machinery between Abnormal Protein Accumulation and Transcriptional Suppression

Abnormal protein accumulation is often observed in human neurodegenerative disorders such as polyglutamine diseases and Parkinson disease. Genetic and biochemical analyses indicate that valosin-containing protein (VCP) is a crucial molecule in the pathogenesis of human neurodegenerative disorders. W...

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Bibliografiska uppgifter
Huvudupphovsmän: Koike, Masaaki, Fukushi, Junpei, Ichinohe, Yuzuru, Higashimae, Naoki, Fujishiro, Masahiko, Sasaki, Chiyomi, Yamaguchi, Masahiro, Uchihara, Toshiki, Yagishita, Saburo, Ohizumi, Hiroshi, Hori, Seiji, Kakizuka, Akira
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2010
Ämnen:
Molecular Bases of Disease
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898386/
https://ncbi.nlm.nih.gov/pubmed/20410307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.099283
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