Valosin-containing Protein (VCP) in Novel Feedback Machinery between Abnormal Protein Accumulation and Transcriptional Suppression

Abnormal protein accumulation is often observed in human neurodegenerative disorders such as polyglutamine diseases and Parkinson disease. Genetic and biochemical analyses indicate that valosin-containing protein (VCP) is a crucial molecule in the pathogenesis of human neurodegenerative disorders. W...

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Hlavní autoři: Koike, Masaaki, Fukushi, Junpei, Ichinohe, Yuzuru, Higashimae, Naoki, Fujishiro, Masahiko, Sasaki, Chiyomi, Yamaguchi, Masahiro, Uchihara, Toshiki, Yagishita, Saburo, Ohizumi, Hiroshi, Hori, Seiji, Kakizuka, Akira
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898386/
https://ncbi.nlm.nih.gov/pubmed/20410307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.099283
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