A carregar...

Structural basis for the binding and incorporation of nucleotide analogs with L-stereochemistry by human DNA polymerase λ

Although lamivudine and emtricitabine, two L-deoxycytidine analogs, have been widely used as antiviral drugs for years, a structural basis for D-stereoselectivity against L-dNTPs, enantiomers of natural nucleotides (D-dNTPs), by any DNA polymerase or reverse transcriptase has not been established du...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Vyas, Rajan, Zahurancik, Walter J., Suo, Zucai
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121797/
https://ncbi.nlm.nih.gov/pubmed/25015085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401286111
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!