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Structural Insights into the Post-Chemistry Steps of Nucleotide Incorporation Catalyzed by a DNA Polymerase

DNA polymerases are essential enzymes that faithfully and efficiently replicate genomic information.(1–3) The mechanism of nucleotide incorporation by DNA polymerases has been extensively studied structurally and kinetically, but several key steps following phosphodiester bond formation remain struc...

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Dades bibliogràfiques
Publicat a:J Am Chem Soc
Autors principals: Reed, Andrew J., Vyas, Rajan, Raper, Austin T., Suo, Zucai
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6634981/
https://ncbi.nlm.nih.gov/pubmed/27959534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b11258
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