Mechanism of Template-independent Nucleotide Incorporation Catalyzed by a Template-dependent DNA Polymerase

Numerous template-dependent DNA polymerases are capable of catalyzing template-independent nucleotide additions onto blunt-end DNA. Such non-canonical activity has been hypothesized to increase the genomic hypermutability of retroviruses including human immunodeficiency viruses. Here, we employed pr...

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Detalhes bibliográficos
Main Authors: Fiala, Kevin A., Brown, Jessica A., Ling, Hong, Kshetry, Ajay K., Zhang, Jun, Taylor, John-Stephen, Yang, Wei, Suo, Zucai
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866274/
https://ncbi.nlm.nih.gov/pubmed/17095011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.10.008
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