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Mechanism of Template-independent Nucleotide Incorporation Catalyzed by a Template-dependent DNA Polymerase
Numerous template-dependent DNA polymerases are capable of catalyzing template-independent nucleotide additions onto blunt-end DNA. Such non-canonical activity has been hypothesized to increase the genomic hypermutability of retroviruses including human immunodeficiency viruses. Here, we employed pr...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2006
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1866274/ https://ncbi.nlm.nih.gov/pubmed/17095011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.10.008 |
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