Glycerol-3-phosphate acyltransferase-4-deficient mice are protected from diet-induced insulin resistance by the enhanced association of mTOR and rictor

Glycerol-3-phosphate acyltransferase (GPAT) activity is highly induced in obese individuals with insulin resistance, suggesting a correlation between GPAT function, triacylglycerol accumulation, and insulin resistance. We asked whether microsomal GPAT4, an isoform regulated by insulin, might contrib...

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Detalhes bibliográficos
Main Authors: Zhang, Chongben, Cooper, Daniel E., Grevengoed, Trisha J., Li, Lei O., Klett, Eric L., Eaton, James M., Harris, Thurl E., Coleman, Rosalind A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121579/
https://ncbi.nlm.nih.gov/pubmed/24939733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00034.2014
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