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Glycerol-3-phosphate acyltransferases: Rate limiting enzymes of triacylglycerol biosynthesis

Four homologous isoforms of glycerol-3-phosphate acyltransferase (GPAT), each the product of a separate gene, catalyze the synthesis of lysophosphatidic acid from glycerol-3-phosphate and long-chain acyl-CoA. This step initiates the synthesis of all the glycerolipids and evidence from gain-of-functi...

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Autores principales: Wendel, Angela A., Lewin, Tal M., Coleman, Rosalind A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737689/
https://ncbi.nlm.nih.gov/pubmed/19038363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2008.10.010
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