Glycerol-3-phosphate Acyltransferase Isoform-4 (GPAT4) Limits Oxidation of Exogenous Fatty Acids in Brown Adipocytes

Glycerol-3-phosphate acyltransferase-4 (GPAT4) null pups grew poorly during the suckling period and, as adults, were protected from high fat diet-induced obesity. To determine why Gpat4(−/−) mice failed to gain weight during these two periods of high fat feeding, we examined energy metabolism. Compa...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Cooper, Daniel E., Grevengoed, Trisha J., Klett, Eric L., Coleman, Rosalind A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Lipids
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463454/
https://ncbi.nlm.nih.gov/pubmed/25918168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.649970
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