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ER Stress-Induced Clearance of Misfolded GPI-Anchored Proteins via the Secretory Pathway

Proteins destined for the cell surface are first assessed in the endoplasmic reticulum (ER) for proper folding before release into the secretory pathway. This ensures that defective proteins are normally prevented from entering the extracellular environment, where they could be disruptive. Here, we...

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Autori principali: Satpute-Krishnan, Prasanna, Ajinkya, Monica, Bhat, Savithri, Itakura, Eisuke, Hegde, Ramanujan S., Lippincott-Schwartz, Jennifer
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121523/
https://ncbi.nlm.nih.gov/pubmed/25083867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.06.026
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