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ER trapping reveals Golgi enzymes continually revisit the ER through a recycling pathway that controls Golgi organization

Whether Golgi enzymes remain localized within the Golgi or constitutively cycle through the endoplasmic reticulum (ER) is unclear, yet is important for understanding Golgi dependence on the ER. Here, we demonstrate that the previously reported inefficient ER trapping of Golgi enzymes in a rapamycin-...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sengupta, Prabuddha, Satpute-Krishnan, Prasanna, Seo, Arnold Y., Burnette, Dylan T., Patterson, George H., Lippincott-Schwartz, Jennifer
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679030/
https://ncbi.nlm.nih.gov/pubmed/26598700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520957112
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