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ER trapping reveals Golgi enzymes continually revisit the ER through a recycling pathway that controls Golgi organization

Whether Golgi enzymes remain localized within the Golgi or constitutively cycle through the endoplasmic reticulum (ER) is unclear, yet is important for understanding Golgi dependence on the ER. Here, we demonstrate that the previously reported inefficient ER trapping of Golgi enzymes in a rapamycin-...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Sengupta, Prabuddha, Satpute-Krishnan, Prasanna, Seo, Arnold Y., Burnette, Dylan T., Patterson, George H., Lippincott-Schwartz, Jennifer
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679030/
https://ncbi.nlm.nih.gov/pubmed/26598700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520957112
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