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ER Stress-Induced Clearance of Misfolded GPI-Anchored Proteins via the Secretory Pathway

Proteins destined for the cell surface are first assessed in the endoplasmic reticulum (ER) for proper folding before release into the secretory pathway. This ensures that defective proteins are normally prevented from entering the extracellular environment, where they could be disruptive. Here, we...

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Autors principals: Satpute-Krishnan, Prasanna, Ajinkya, Monica, Bhat, Savithri, Itakura, Eisuke, Hegde, Ramanujan S., Lippincott-Schwartz, Jennifer
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121523/
https://ncbi.nlm.nih.gov/pubmed/25083867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.06.026
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