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ER Stress-Induced Clearance of Misfolded GPI-Anchored Proteins via the Secretory Pathway

Proteins destined for the cell surface are first assessed in the endoplasmic reticulum (ER) for proper folding before release into the secretory pathway. This ensures that defective proteins are normally prevented from entering the extracellular environment, where they could be disruptive. Here, we...

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Détails bibliographiques
Auteurs principaux: Satpute-Krishnan, Prasanna, Ajinkya, Monica, Bhat, Savithri, Itakura, Eisuke, Hegde, Ramanujan S., Lippincott-Schwartz, Jennifer
Format: Artigo
Langue:Inglês
Publié: Cell Press 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121523/
https://ncbi.nlm.nih.gov/pubmed/25083867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.06.026
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