Limited ER quality control for GPI-anchored proteins

Endoplasmic reticulum (ER) quality control mechanisms target terminally misfolded proteins for ER-associated degradation (ERAD). Misfolded glycophosphatidylinositol-anchored proteins (GPI-APs) are, however, generally poor ERAD substrates and are targeted mainly to the vacuole/lysosome for degradatio...

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Detalles Bibliográficos
Publicado en:J Cell Biol
Autores principales: Sikorska, Natalia, Lemus, Leticia, Aguilera-Romero, Auxiliadora, Manzano-Lopez, Javier, Riezman, Howard, Muñiz, Manuel, Goder, Veit
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915193/
https://ncbi.nlm.nih.gov/pubmed/27325793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201602010
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