Liposomes Containing Monophosphoryl Lipid A: A Potent Adjuvant System For Inducing Antibodies To Heroin Hapten Analogs

In order to create an effective immunization approach for a potential vaccine to heroin, liposomes containing monophosphoryl lipid A [L(MPLA)] were tested as an adjuvant system to induce antibodies to heroin hapten analogs. Four synthetic haptens and two immunization strategies were employed. In the...

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Main Authors: Matyas, Gary R., Mayorov, Alexander V., Rice, Kenner C., Jacobson, Arthur E., Cheng, Kejun, Iyer, Malliga R., Li, Fuying, Beck, Zoltan, Janda, Kim D., Alving, Carl R.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120113/
https://ncbi.nlm.nih.gov/pubmed/23624097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2013.04.027
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