Facial recognition of heroin vaccine opiates: Type 1 cross-reactivities of antibodies induced by hydrolytically stable haptenic surrogates of heroin, 6-acetylmorphine, and morphine

Novel synthetic compounds similar to heroin and its major active metabolites, 6-acetylmorphine and morphine, were examined as potential surrogate haptens for the ability to interface with the immune system for a heroin vaccine. Recent studies have suggested that heroin-like haptens must degrade hydr...

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Autors principals: Matyas, Gary R., Rice, Kenner C., Cheng, Kejun, Li, Fuying, Antoline, Joshua F. G., Iyer, Malliga R., Jacobson, Arthur E., Mayorov, Alexander V., Beck, Zoltan, Torres, Oscar, Alving, Carl R.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090106/
https://ncbi.nlm.nih.gov/pubmed/24486371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.01.028
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